Climbazole mainly blocks lanosterol 14 in P450 enzyme by non competitive way α- The synthesis of demethylase (also known as fungal CYP51), thereby inhibiting the biosynthesis of ergosterol, an important component of plasma fungal cell membrane, and causing fungal cell death.
Multiple Names
1-(4-Clorophenoxy)-3,3-Dimethyl-1-(Imidazole-1-Yl)-2-Butanone;
1-(4-Chlorophenoxy)-1-(1H-Imidazol-1-Yl)-3,3-Dimethylbutan-2-One
CAS No. 38083-17-9
EC No. 253-775-4
MF No. C15H17ClN2O2
MW No. 292.7607
Assay Item | Standard |
Form | Neat |
Color | White to almost white |
Boiling Point | 96-100°C |
Melting Point | 447.5±40.0 °C(Predicted) |
Density | 1.17±0.1 g/cm3(Predicted) |
LogP | 3.83 at 25℃ |
Anti dandruff effect.
It does not induce micronuclei in human lymphocytes.
It has broad-spectrum bactericidal performance, anti-itching and anti dandruff conditioning shampoo, hair care shampoo, antibacterial soap, shower gel, medicated toothpaste, mouthwash, etc.
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